What causes medication-induced dystonic reactions?

Updated: Feb 19, 2018
  • Author: John Michael Kowalski, DO; Chief Editor: David Vearrier, MD, MPH  more...
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Neuroleptics (antipsychotics), antiemetics, and antidepressants are the most common causes of drug-induced dystonic reactions. [10, 11, 12, 13, 14] Acute dystonic reactions have been described with every antipsychotic. Alcohol and cocaine use increase risk. [15, 16] Cases involving other drugs have been reported, including methylphenidate and carbamazepine. [17, 18]

Predisposing factors include a family history of dystonia and viral infection.

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