Which agents have similar toxicity presentations to cyanide poisoning?

Updated: May 30, 2020
  • Author: Inna Leybell, MD; Chief Editor: Michael A Miller, MD  more...
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Consider the diagnosis of cyanide poisoning in patients with rapid collapse or seizures accompanied by metabolic acidosis and decreased oxygen consumption. Other agents that may have similar features in toxicity include the following [9] :

  • Arsine

  • Inert gases (simple asphyxiants)

  • Metformin

  • Monomethylhydrazine

  • Organophosphorus compounds

  • Phosphine

The Chemical terrorism agents and syndromes: signs and symptoms sheet (copyright University of North Carolina at Chapel Hill) provides a comparison of presentations seen with different chemical terrorism agents at different degrees and routes of exposure.

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