Which musculoskeletal findings are characteristic of cocaine toxicity?

Updated: Sep 01, 2018
  • Author: Lynn Barkley Burnett, MD, EdD, LLB(c); Chief Editor: Sage W Wiener, MD  more...
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Answer

Cocaine use is among the drug-related causes of intrinsic muscle weakness. Wilson and Hobbs report a patient with Cori disease in whom cocaine unmasked subclinical skeletal muscle weakness, causing prolonged respiratory muscle insufficiency. Cocaine has also been implicated as a cause of impairment of neuromuscular transmission in a patient with myasthenia gravis.


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