What is the pathophysiology of cocaine toxicity?

Updated: Sep 01, 2018
  • Author: Lynn Barkley Burnett, MD, EdD, LLB(c); Chief Editor: Sage W Wiener, MD  more...
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Answer

Tachydysrhythmias cause most acute cocaine-related nontraumatic deaths. Other causes of sudden death include stroke, subarachnoid hemorrhage, hyperthermia, and the consequences of agitated delirium. Myocardial infarction (MI) can result from acute vasospasm, dysrhythmia, or chronic accelerated atherogenic disease.


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