What monitoring is indicated in patients receiving thrombolytic therapy for acute ischemic stroke (AIS)?

Updated: Aug 04, 2021
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Patients receiving thrombolytic therapy for AIS must undergo constant neurologic and cardiovascular reevaluation. Blood pressure must be checked every 15 minutes during and after tPA infusion for 2 hours, then every 30 minutes for 6 hours and finally every hour for the next 16 hours after tPA infusion. [59] Strict blood pressure monitoring is essential to prevention of complications. If a patient has signs of neurologic deterioration, stop thrombolytic therapy and obtain emergency computed tomography (CT). Consider immediate expert consultation.

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