What is the role of thrombolytic therapy in the treatment of peripheral arterial disease (PAD)?

Updated: Aug 04, 2021
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Accepted treatments for prompt revascularization consist of catheter-directed thrombolysis (CDT), percutaneous mechanical thrombus extraction with or without thrombolytic therapy, and surgical thrombectomy or bypass.

Primary fibrinolysis is the initial treatment of choice for many patients with acute peripheral arterial occlusions. The ability to perform CDT with subsequent angioplasty and stenting has reduced the need for arterial surgery in many settings.

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