What is the efficacy of thrombolytic therapy in elderly patients with acute ischemic stroke (AIS)?

Updated: Dec 31, 2017
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Answer

Answer

Because strokes occur predominantly in the elderly population, decreasing benefit from thrombolysis with age is a concern. However, the International Stroke Trial 3 (IST3) found no direct association between alteplase administration and hemorrhage rate in the elderly patients selected by means of noncontrast computed tomography (CT). [47]


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