What is the FDA recommended regimen of reteplase for thrombolytic therapy of pulmonary embolism (PE)?

Updated: Dec 31, 2017
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Answer

Answer

Reteplase has not been approved by the FDA for any indication except AMI, but it is widely used for acute deep vein thrombosis (DVT) and PE. The dosing used is the same as that approved for patients with AMI: two IV boluses of 10 U each, administered 30 minutes apart.


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