What are the thrombolytic therapy regimens for reteplase in patients with acute myocardial infarction (AMI)?

Updated: Dec 31, 2017
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
  • Print
Answer

Answer

First, reconstitute two 10-unit vials with sterile water (10 mL) to 1 U/mL. The adult dose of reteplase for AMI consists of two IV boluses of 10 units each; there is no weight adjustment. The first 10-unit IV bolus is given over 2 minutes; 30 minutes later, a second 10-unit IV bolus is given over 2 minutes. Administer normal saline (NS) flush before and after each bolus.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!