What is the mainstay of thrombolytic therapy for ST-segment elevation MI (STEMI)?

Updated: Aug 04, 2021
  • Author: Wanda L Rivera-Bou, MD, FAAEM, FACEP; Chief Editor: Erik D Schraga, MD  more...
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Patients with STEMI usually have complete occlusion of an epicardial coronary vessel caused by an acute thrombotic obstruction. The earlier the patient presents, and the earlier the artery can be recanalized, the better.

The mainstay of treatment is reperfusion therapy involving either administration of fibrinolytics (pharmacologic reperfusion) or primary percutaneous coronary intervention (PCI; ie, mechanical reperfusion).

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