What are the benefits of early prone positioning during mechanical ventilation in patients with severe acute respiratory distress syndrome (ARDS)?

Updated: Apr 07, 2020
  • Author: Allon Amitai, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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In a recent prospective, randomized, controlled trial, Guerin et al examined whether early prone positioning during mechanical ventilation can improve outcomes in patients with severe ARDS. The authors found that both the 28-day and unadjusted 90-day mortalities in the prone group were significantly lower (16% and 23.6%, respectively) than in the supine group (32.8% and 41%, respectively). [19] Although they found no difference between the groups with regard to duration of invasive mechanical ventilation or length of stay in the ICU, they found a higher incidence of cardiac arrest in the supine group (31% vs 16% in the prone group).

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