Which medications in the drug class Benzodiazepines are used in the treatment of Temporomandibular Joint (TMJ) Syndrome?

Updated: Jun 02, 2020
  • Author: Vivian Tsai, MD, MPH, FACEP; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Benzodiazepines

Used for muscle relaxant properties but relatively contraindicated in pediatric patients because of sedating properties; appear to potentiate effects of GABA and facilitate inhibitory GABA neurotransmission and other inhibitory transmitters by binding to specific receptor sites.

Diazepam (Valium)

Depresses all levels of CNS, including limbic and reticular formation, possibly by increasing activity of GABA, a major inhibitory neurotransmitter.

Individualize dosage and increase cautiously to avoid adverse effects.


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