What is the role of medications in the treatment of pneumonia in immunocompromised patients?

Updated: Jan 07, 2019
  • Author: Julie B Zhao, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Answer

Pharmacologic therapy consists mainly of empiric antibiotics awaiting results of diagnostic studies.

Taking into consideration each patient's characteristics and risk factors, a narrow differential diagnosis can be established and help tailor therapy to the most likely organism and prevent overuse of anti-microbe therapy.

A meta-analysis by Wang et al indicated that in HIV-infected patients with P jiroveci pneumonia, early adjunctive corticosteroid treatment may lead to a 0.55 times reduced risk of mortality compared with patients who do not receive the adjunctive therapy. [62]


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