How is glucose assessment of CSF from lumbar puncture (LP) used in the diagnosis of infection?

Updated: Aug 02, 2018
  • Author: Gil Z Shlamovitz, MD, FACEP; Chief Editor: Helmi L Lutsep, MD  more...
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Answer

The CSF glucose level normally approximates 60% of the peripheral blood glucose level at the time of the tap. A simultaneous measurement of blood glucose (especially if the CSF glucose level is likely to be low) is recommended. A low CSF glucose level is usually associated with bacterial infection but is also seen in tumor infiltration. A high CSF glucose level has no specific diagnostic significance and is most often spillover from an elevated blood glucose level.


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