Which medications are used for pediatric procedural sedation?

Updated: May 08, 2018
  • Author: Wan-Tsu Wendy Chang, MD; Chief Editor: Ted Rosenkrantz, MD  more...
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Medications for procedural sedation include the following:

  • Opioid analgesics – Morphine sulfate, fentanyl

  • Benzodiazepines – Midazolam, diazepam

  • Barbiturates – Pentobarbital, methohexital, thiopental

  • Miscellaneous agents – Nitrous oxide, ketamine, propofol, dexmedetomidine

Although the medication dose is calculated based on weight, the response can vary significantly from one child to the next. Appropriate actions include the following:

  • Consider starting with the lowest recommended dose (or even half that) and titrate as needed

  • Keep reversal agents, when available, at the bedside, and double-check their proper doses

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