Which medications are used in the treatment of pediatric pyloric stenosis?

Updated: Nov 13, 2018
  • Author: Sathyaseelan Subramaniam, MD, FAAP; Chief Editor: Kirsten A Bechtel, MD  more...
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  • Nonsurgical treatment for infantile hypertrophic pyloric stenosis with atropine sulfate, either intravenous or oral, is an alternative in the rare case that general anesthesia or surgery is contraindicated. In a systematic review that identified 10 studies, treatment with atropine had a lower success rate and longer duration of therapy compared to conventional pyloromyotomy. [16]
  • A recent nationwide review of pyloric stenosis management with atropine in Japan echoed similar findings – they found that surgical intervention has a higher success rates, minimal complications and shorter duration of hospital stay compared to atropine therapy. [17]

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