How is the risk of sepsis minimized in pediatric patients with sickle cell disease (SCD) and fever?

Updated: Jul 23, 2019
  • Author: Hina Z Ghory, MD; Chief Editor: Russell W Steele, MD  more...
  • Print
Answer

Answer

Patients with sickle cell disease (SCD) are considered functionally asplenic. Asplenic patients are at exceptional high risk of sepsis due to encapsulated organisms, such as Streptococcus pneumonia. Because of this, patients with SCD are often hospitalized for observation and empiric treatment. If these patients present with fever, they are considered at higher risk for occult bacteremia and treated accordingly. Blood cultures, CBCs, and differentials are assessed. Parenteral antibiotics against encapsulated organisms are given early.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!