What causes dacryoadenitis?

Updated: Jul 31, 2018
  • Author: Bobak Zonnoor , MD; Chief Editor: Gil Z Shlamovitz, MD, FACEP  more...
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Dacryoadenitis is caused by local infection of the lacrimal gland by bacteria or viruses. Chronic dacryoadenitis associated with inflammation and swelling of the salivary glands of unknown origin is called Mikulicz disease. When associated with other entities such as tuberculosis, sarcoidosis, or lymphoma, it is termed Mikulicz syndrome. This was previously considered a subtype of Sjögren syndrome, although now differences between the 2 entities have been determined. [33]


Dacryoadenitis is most often caused by gram-positive cocci, usually staphylococci. It may also be caused by S pneumoniae.


Prior to increased immunization rates, the mumps virus was most often implicated in the development of dacryoadenitis. Now, the Epstein-Barr virus is most often associated with chronic dacryoadenitis. [34]

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