Which medications in the drug class Anticholinergic Agents, Ophthalmic are used in the treatment of Iritis and Uveitis?

Updated: Jan 15, 2019
  • Author: Monalisa N Muchatuta , MD, MS; Chief Editor: Gil Z Shlamovitz, MD, FACEP  more...
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Answer

Anticholinergic Agents, Ophthalmic

These agents block nerve impulses to the pupillary sphincter and ciliary muscles, easing pain and photophobia.

Cyclopentolate 0.5-2% (Cyclogyl)

Induces cycloplegia in 25-75 min and mydriasis in 30-60 min. Effects last as long as 1 d; however, duration may be less in setting of severe anterior chamber reaction. For this reason, Cyclogyl less attractive for treating uveitis than homatropine.

Homatropine (Isopto Homatropine, Homatropaire)

Induces cycloplegia in 30-90 min and mydriasis in 10-30 min. Effects last 10-48 h for cycloplegia and 6 h to 4 d for mydriasis, but duration may be less in setting of severe anterior chamber reaction. Homatropine is agent of choice for uveitis.


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