Which medications in the drug class Antirheumatic, disease-modifying agents are used in the treatment of Corneal Ulcer and Ulcerative Keratitis in Emergency Medicine?

Updated: Nov 08, 2018
  • Author: Jesse Borke, MD, FACEP, FAAEM; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Antirheumatic, disease-modifying agents

These agents are used in the treatment of rheumatoid arthritis associated corneal ulcer.

Infliximab (Remicade, Inflectra, Renflexis)

Chimeric anti-tumor necrosis factor alpha monoclonal antibody. Neutralizes cytokine TNF-alpha and inhibits its binding to TNF-alpha receptor. Mix in 250-mL normal saline for infusion over 2 h. Must use with low-protein-binding filter (1.2 micron or less). Indicated to reduce signs and symptoms of active ankylosing spondylitis.


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