Which medications in the drug class Analgesics are used in the treatment of Corneal Ulcer and Ulcerative Keratitis in Emergency Medicine?

Updated: Nov 08, 2018
  • Author: Jesse Borke, MD, FACEP, FAAEM; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Analgesics

Pain control is essential to quality patient care, ensuring patient comfort, promoting pulmonary toilet, and containing sedating properties that benefit patients who experience mild or severe pain.

Oxycodone and acetaminophen (Percocet, Endocet, Primlev, Xartemis XR)

Drug combination indicated for the relief of moderate to severe pain. Oxycodone inhibits ascending pain pathways by binding to the opiate receptor. Alters the response and perception of pain and produces generalized CNS depression. Acetaminophen inhibits prostaglandin synthesis in the CNS and blocks pain impulse generation peripherally.

Oxycodone and aspirin (Percodan)

This drug combination is indicated for the relief of moderate to severe pain. Oxycodone binds to opiate receptors in the central nervous system (CNS), inhibiting the ascending pain pathways, altering pain response and perception. Aspirin inhibits platelet aggregation; has analgesic and ant-inflammatory properties.

Morphine (Arymo ER, Duramorph, Kadian, MS Contin)

An opioid analgesic, morphine interacts with endorphin receptors in the CNS, inhibiting the pain pathways, altering pain response and perception.

Codeine and acetaminophen (Tylenol with Codeine #3, Tylenol with Codeine #4)

Acetaminophen and codeine combination is used for the treatment of mild to moderate pain.

Hydrocodone and acetaminophen (Hycet, Lorcet, Norco, Vicodin, Zamicet)

This combination is used for the relief of moderate to severe pain. Analgesics alter the perception of and response to pain.


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