What is the role of liquid chromatography in the workup of Wernicke encephalopathy (WE)?

Updated: Nov 20, 2018
  • Author: Philip N Salen, MD; Chief Editor: Andrew K Chang, MD, MS  more...
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Answer

This thiamine assay is now commercially available in many countries. Adult normal range (60–220 nM) and the lowest detectable level (3–35 nM) are given. The sample (2 ml EDTA blood) should be taken before administration of thiamine and should be protected from light. [1] This assay has largely supplanted the erythrocyte transketolase assay.


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