What are the IASP diagnostic criteria for complex regional pain syndrome II (CRPS II)?

Updated: Nov 08, 2018
  • Author: Steven J Parrillo, DO, FACOEP, FACEP; Chief Editor: Andrew K Chang, MD, MS  more...
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According to the IASP, CRPS II (also known as causalgia) is diagnosed as follows:

  1. The presence of continuing pain, allodynia, or hyperalgesia after a nerve injury, not necessarily limited to the distribution of the injured nerve

  2. Evidence at some time of edema, changes in skin blood flow, or abnormal sudomotor activity in the region of pain

  3. The diagnosis is excluded by the existence of any condition that would otherwise account for the degree of pain and dysfunction.

Several authors note that these diagnostic criteria show high sensitivity but low specificity. [23]

Note that the primary difference between type I and type II is the identification of a definable nerve injury.

Two other criteria sets are in common use for CRPS I, though the IASP only accepts the above criteria. While there is overlap, the differences have caused some difficulties in that authors may define their populations differently. [24]

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