Which age groups have the highest prevalence of complex regional pain syndrome (CRPS)?

Updated: Nov 08, 2018
  • Author: Steven J Parrillo, DO, FACOEP, FACEP; Chief Editor: Andrew K Chang, MD, MS  more...
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Persons of all ages are affected. Stanton-Hicks reports that in contrast to adults, 90% of pediatric cases occur in female children aged 8-16 years, with the youngest being 3 years. That author and others report that CRPS is treated most effectively in pediatric patients, with a remission rate of 97%. [16, 17]

An Israeli group suggested that CRPS in children and adolescents is underdiagnosed. They emphasize the importance of early recognition and multidisciplinary treatment. [18]

Several have looked into the possibility that there may be an increased risk of CRPS development in siblings. de Rooij et al showed that, although the overall risk is not increased, the risk in siblings younger than 50 years is significantly increased. [19, 20]

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