How is a diagnosis of dementia confirmed?

Updated: Sep 19, 2018
  • Author: Richard D Shin, MD; Chief Editor: Gil Z Shlamovitz, MD, FACEP  more...
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Answer

A postmortem examination of the brain is currently the only way to positively diagnose the various dementing illnesses.

A blood test for apolipoprotein E (ApoE) subtype e4 is still under study, but it promises to greatly enhance diagnostic accuracy for AD.

Researchers at the Stanford University School of Medicine developed a blood test that may someday be a step toward predicting AD 2-6 years in advance of onset. The test identifies changes in certain blood proteins that cells use to convey messages to one another and has a 90% positive predictive value. [16]


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