Which findings suggest herpes simplex virus (HSV) infection in neonates with encephalitis?

Updated: Aug 07, 2018
  • Author: David S Howes, MD; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Findings of herpes simplex virus (HSV) infection in neonates may include the following:

  • Herpetic skin lesions over the presenting surface from birth or with breaks in the skin, such as those resulting from fetal scalp monitors

  • Keratoconjunctivitis

  • Oropharyngeal involvement, particularly buccal mucosa and tongue

  • Encephalitis symptoms (eg, seizures, irritability, change in attentiveness, and bulging fontanelles)

  • Additional signs of disseminated, severe HSV include jaundice, hepatomegaly, and shock

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