How is pseudobulbar affect treated in patients with amyotrophic lateral sclerosis (ALS)?

Updated: Jul 20, 2021
  • Author: Ryan Ghusayni, MD; Chief Editor: Andrew K Chang, MD, MS  more...
  • Print


Pseudobulbar affect, excessive laughing or crying or involuntary emotional expression, affects 20-50% of patients with ALS. [9] combined dextromethorphan and quinidine has been administered for this condition [10] . This drug combination was approved by the FDA in October 2010.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!