What is the role of riluzole in the treatment of amyotrophic lateral sclerosis (ALS)?

Updated: Nov 13, 2019
  • Author: Kathleen Clem, MD, FACEP; Chief Editor: Andrew K Chang, MD, MS  more...
  • Print
Answer

Answer

Riluzole is the only current disease-specific medication approved by the US Food and Drug Administration (FDA) for use in patients with ALS. It should be prescribed only by a physician familiar with inclusion/exclusion criteria and who will be monitoring patient. It should not be prescribed in the ED acutely. [1, 4]

For patients who develop fatigue while taking riluzole, withholding the drug may be considered.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!