What are the signs and symptoms of Colorado tick fever?

Updated: Aug 05, 2019
  • Author: Shawn J Sethi, DO; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Symptoms of Colorado tick fever typically begin 4-5 days after the tick bite, although incubation periods as long as 20 days have been reported. Free virus can be isolated from the blood for the first 2 weeks of illness. Following the initial period, the virus then circulates inside erythropoietic cells. The virus can live in a red blood cell for the life of the cell, which is approximately 120 days. Thus, blood donation from affected individuals is prohibited for 6 months after infection.

Cases with prominent hepatic or central nervous system (CNS) manifestations have been reported. Transfusion-associated cases from viremic patients have occurred. [5]

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