What is the mortality and morbidity associated with Salmonella infections?

Updated: Aug 10, 2018
  • Author: Michael D Owens, DO, MPH, FACEP, FAAEM; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Answer

Twenty percent of patients require hospitalization, with an estimated death rate of 0.6%. [17] Infection with drug-resistant nontyphoid Salmonella and Salmonella typhi increase the likelihood of hospitalization and death. [17]

Invasive nontyphoid Salmonella infection occurs in about 5% of cases in Israel [17] and is responsible for 400-600 deaths in the United States each year. [5] In 2010, the CDC reported Salmonella infection was the most common foodborne disease in the United States and was associated with the most hospitalizations and deaths. [15] Mortality for nontyphoid Salmonella a is reported to be as high as 60% in African patients with HIV. [22] Mycotic abdominal aortic aneurysms are more common in immunocompromised and HIV patients.

Treated typhoid cases have a 2% mortality rate with a 15% relapse rate. [3] A significant number of typhoid patients become chronic asymptomatic carriers and can shed high numbers of bacteria in the stool for a lifetime without obvious symptoms. [22] Depending on the serotype, roughly 1% of adults and 5% of children excrete organisms for greater than a year. [23]


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