Which lab studies are performed following a needle-stick exposure?

Updated: Jul 01, 2021
  • Author: Megan A Stobart-Gallagher, DO; Chief Editor: Jeter (Jay) Pritchard Taylor, III, MD  more...
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Answer

Laboratory studies in the source patient (if available) are as follows:

  • HIV testing
  • Hepatitis B antigen
  • Hepatitis C antibody
  • Aspartate aminotransferase/alanine aminotransferase (AST/ALT) and alkaline phosphatase levels

Laboratory studies in exposed individuals/health care worker include the following:

  • Hepatitis B surface antibody
  • HIV testing at time of incident and again at 6 weeks, 3 months, and 6 months
  • Hepatitis C antibody at time of incident and again at 2 weeks, 4 weeks, and 8 weeks

The following are laboratory studies to be performed prior to initiating retroviral therapy:

  • Pregnancy test
  • CBC count with differential and platelets
  • Serum creatinine/BUN levels
  • Urinalysis with microscopic analysis
  • AST/ALT levels
  • Alkaline phosphatase level
  • Total bilirubin level

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