When is platelet transfusion indicated in the treatment of immune thrombocytopenia (ITP)?

Updated: Dec 14, 2019
  • Author: Michael A Silverman, MD, MD; Chief Editor: Gil Z Shlamovitz, MD, FACEP  more...
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Answer

Platelet transfusion is indicated for controlling severe hemorrhage. Send a blood specimen to the lab for type and screen in case platelet transfusion is necessary. Platelet survival is increased if the platelets are transfused immediately after IVIG infusion. A consultation with a hematologist may be required to make a decision regarding the transfusion of platelets.

Guidelines for transfusion dosage are as follows:

  • 6-8 U of platelet concentrate, or 1 U/10 kg
  • 1 U of platelets to increase count of a 70-kg adult by 5-10,000/mm 3 and an 18-kg child by 20,000/mm 3

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