Which medications in the drug class Monoclonal Antibodies are used in the treatment of Hemophilia B?

Updated: Oct 02, 2020
  • Author: Robert A Zaiden, MD; Chief Editor: Srikanth Nagalla, MD, MS, FACP  more...
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Monoclonal Antibodies

These agents are monoclonal antibodies directed against the CD20 antigen on B cells. They are recommended as second-line therapy in the treatment of factor IX inhibitors, especially in cases with high inhibitor titers.

Rituximab (Rituxan)

Rituximab binds to, and mediates destruction of, B-cells, thereby decreasing production of inhibitors and autoimmunization.

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