What are the physical findings characteristic of hemophilia A?

Updated: Apr 08, 2020
  • Author: Douglass A Drelich, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Organ system–specific signs and symptoms of hemorrhage include the following:

  • Musculoskeletal (joints) - Tenderness, pain with movement, decreased range of motion, effusion, and warmth

  • Central nervous system (CNS) - Abnormal neurologic exam findings, altered mental status, and meningismus

  • Gastrointestinal (GI) - Can be painless; hepatic/splenic tenderness, and peritoneal signs

  • Genitourinary - Bladder spasm/distension/pain and costovertebral angle pain

  • Other - Hematoma leading to location-specific signs (eg, airway obstruction, compartment syndrome)

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