What are the signs and symptoms of hemorrhage in hemophilia A?

Updated: Apr 08, 2020
  • Author: Douglass A Drelich, MD; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Signs and symptoms of hemorrhage include the following:

  • General - Weakness and orthostasis

  • Musculoskeletal (joints) - Tingling, cracking, warmth, pain, stiffness, refusal to use the joint (young children)

  • Central nervous system (CNS) - Headache, stiff neck, vomiting, lethargy, irritability, spinal cord syndromes

  • Gastrointestinal (GI) - Hematemesis, melena, frank red blood per rectum, abdominal pain

  • Genitourinary - Hematuria, renal colic, post-circumcision bleeding

  • Other - Epistaxis, oral mucosal hemorrhage, hemoptysis, dyspnea (hematoma leading to airway obstruction), compartment syndrome symptoms, contusions, excessive bleeding with routine dental procedures

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