Which medications are used in the treatment of orchitis?

Updated: Aug 16, 2017
  • Author: Nataisia Terry, MD; Chief Editor: Erik D Schraga, MD  more...
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No medications are indicated for the treatment of viral orchitis.

Bacterial orchitis or epididymo-orchitis requires appropriate antibiotic coverage for suspected infectious agents. In patients with a bacterial etiology who are younger than 35 years and sexually active, antibiotic coverage for sexually transmitted pathogens (particularly gonorrhea and chlamydia) with ceftriaxone [3] and either doxycycline [3] or azithromycin is appropriate. Fluoroquinolones are no longer recommended by the Centers for Disease Control and Prevention (CDC) for treatment of gonorrhea because of resistance. For more information see, CDC updated gonococcal treatment recommendations (April 2007).

Patients older than 35 years with bacterial etiology require additional coverage for other gram-negative bacteria with a fluoroquinolone or trimethoprim-sulfamethoxazole. Other appropriate medications include analgesics or antiemetics, as needed.

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