Which lab tests are indicated to assess for evidence of rejection following liver transplantation?

Updated: Dec 31, 2017
  • Author: Lemi Luu, MD, RDMS, FACEP, FAAEM; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Laboratory studies

In all but minor complaints, the following laboratory tests are indicated to assess for evidence of rejection, effects of azathioprine on bone marrow function, and effects of cyclosporine or tacrolimus on renal function:

  • Complete blood count
  • Electrolyte panel
  • Blood urea nitrogen and creatinine levels
  • Liver function panel
  • Cyclosporine or tacrolimus level: Obtain in the presence of renal dysfunction or if rejection is suspected
  • Cultures of blood, urine, pharynx, and/or sputum: Obtain if infection is suspected

Imaging studies

  • Chest radiography: Obtain in the presence of fever, cough, dyspnea, or abnormalities on chest examination
  • Abdominal ultrasonography, computed tomography scan, or endoscopic retrograde cholangiopancreatography, as indicated

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