Which medications are used to treat anal fissures?

Updated: Nov 09, 2018
  • Author: Bruce M Lo, MD, MBA, CPE, RDMS, FACEP, FAAEM, FACHE; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Medications may also be prescribed for anal fissures, such as topical nitrates, calcium channel blockers, and onabotulinumtoxinA injections, and are considered first-line therapy. [17] These medications reduce anal sphincter tone or vasodilate, which, in turn, increases anodermal blood flow. When conservative treatment fails, surgical therapy may be an option to treat anal fissures.

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