What is the role of procalcitonin measurement in the workup of acute cholangitis?

Updated: Dec 29, 2017
  • Author: Timothy M Scott, DO; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Procalcitonin may have potential as a useful biomarker for determining the need for emergency biliary drainage and intensive care  in patients with acute cholangitis. [12] Shinya et al noted that significantly elevated procalcitonin levels were found in their cohort of patients with grade III inflammation based on the 2013 Tokyo guidelines versus those with grade I inflammation, as well as those with positive hemocultures compared to those with negative hemocultures. Moreover, procalcitonin levels were significantly increased in severe cases that were underestimated as grade I or II. [12]

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