Which factors are used to predict mortality risk for acute cholangitis?

Updated: Dec 29, 2017
  • Author: Timothy M Scott, DO; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Answer

Schneider et al proposed a risk prediction model for in-hospital mortality in patients with acute cholangitis using 22 predictors and the Tokyo criteria to stratify them into high- and low-risk mortality groups and then into different management groups. [8] In univariate analysis, organ failure had the strongest association with mortality—with mental confusion, hypotension requiring catecholamines, Quick value below 50%, serum creatinine level above 2 mg/dL, and a platelet count below 100,000/mm3 as prognostic factors contributing to organ failure. Patients classified as low risk for mortality would be considered for elective biliary drainage, whereas those considered to be at high risk for mortality would undergo urgent biliary drainage. [8]


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