What is the primary sclerosing cholangitis?

Updated: Dec 29, 2017
  • Author: Timothy M Scott, DO; Chief Editor: Barry E Brenner, MD, PhD, FACEP  more...
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Primary sclerosing cholangitis is a chronic liver disease that is thought to be due to an autoimmune mechanism. [2] It is characterized by inflammation and fibrosis of the intrahepatic and extrahepatic bile ducts. This condition ultimately leads to portal hypertension and cirrhosis of the liver with the only definitive treatment being a liver transplant. [3] For more on this condition, please refer to the Primary Sclerosing Cholangitis article.

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