Which medications are used in the treatment of smoke inhalation injury?

Updated: Oct 15, 2021
  • Author: Keith A Lafferty, MD; Chief Editor: Joe Alcock, MD, MS  more...
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The primary treatment of smoke inhalation injury is oxygen. Bronchodilators may be of benefit in patients displaying bronchospasm. In addition, specific antidotes are methylene blue for methemoglobinemia and thiosulfate/sodium nitrite for cyanide (CN) poisoning. Certain patients with carbon monoxide (CO) toxicity may require hyperbaric oxygen therapy (HBO).

Oxygen is used for any suspected significant inhalation injury. Treat with high concentrations of humidified oxygen en route to the hospital.

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