What are the possible neurological sequelae of cyanide toxicity from smoke inhalation?

Updated: Oct 15, 2021
  • Author: Keith A Lafferty, MD; Chief Editor: Joe Alcock, MD, MS  more...
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Consider CN toxicity in all patients with smoke inhalation who have CNS or cardiovascular findings. CN toxicity is difficult to confirm but is frequently concomitant with CO toxicity. Its presence can be inferred by the presence of lactic acidosis in the right clinical setting. Even mild degrees of CN poisoning can cause delayed neurological sequelae in survivors and permanent disability including the following:

  • Seizures

  • Various extrapyramidal syndromes

  • Dystonia

  • Postanoxic coma

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