What are the mechanisms of smoke inhalation injury?

Updated: Oct 15, 2021
  • Author: Keith A Lafferty, MD; Chief Editor: Joe Alcock, MD, MS  more...
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The 3 primary mechanisms that lead to injury in smoke inhalation are thermal damage, asphyxiation, and pulmonary irritation. The combination of these mechanisms can explain the pathophysiologic responses that alter the airway microenvironment with parenchymal damage and predispose smoke inhalation victims to respiratory insufficiency.

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