Which medications in the drug class Corticosteroid, Systemic are used in the treatment of Insect Bites?

Updated: Jun 21, 2018
  • Author: Boyd (Bo) D Burns, DO, FACEP, FAAEM; Chief Editor: Joe Alcock, MD, MS  more...
  • Print

Corticosteroid, Systemic

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. In addition, these agents modify the body's immune response to diverse stimuli. Prednisone and methylprednisolone are typical drugs of this class. Oral bioavailability is generally similar to parenteral; administer oral prednisone when indicated if a patient is not in extremis and can comfortably take it orally; administer parenteral steroids when indicated for a patient in more severe circumstances.


Prednisone is believed to ameliorate delayed effects of anaphylactic reactions and may limit biphasic anaphylaxis. Doses are general guidelines for usage; dosing is highly individualized.

Methylprednisolone (Solu-Medrol, Depo-Medrol)

Methylprednisolone is useful for treating inflammatory and allergic reactions. By reversing increased capillary permeability and suppressing PMN activity, it may decrease inflammation. A multitude of corticosteroid preparations is available. Methylprednisolone is widely available in the ED because of its other uses (ie, acute asthma, spinal cord injury) and is supplied in both parenteral and oral formulations.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!