Which medications in the drug class Vaccine, Inactivated Virus are used in the treatment of Animal Bites in Emergency Medicine?

Updated: Sep 18, 2018
  • Author: Alisha Perkins Garth, MD; Chief Editor: Joe Alcock, MD, MS  more...
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Answer

Vaccine, Inactivated Virus

Inactivated virus vaccines are inactivated forms of virus that promote immunity by inducing an active immune response.

Rabies vaccine (Rabavert, Imovax Rabies Vaccine)

Rabies vaccine is an inactivated form of virus grown in primary cultures of chicken fibroblasts; it offers active immunity and, when used in combination with human rabies immune globulin (HRIG) and local wound treatment, protects postexposure patients of all age groups; it is also used for preexposure immunization in both the primary series and booster dose.

Fourteen days after initiating immunization series, anti-rabies antibody titers reach levels well abovethe minimal protective level of 0.5 IU/mL.

The vaccine must be injected intramuscularly and never SC, ID, or IV. In adults, inject into the deltoid muscle area. In small children, administer into the anterolateral zone of the thigh.

Rabies vaccine (HDCV, Imovax, Rabies vaccine human diploid cell culture)

Rabies vaccine adsorbed is an inactivated virus vaccine that promotes immunity by inducing active immune response. Rabies vaccine is given intramuscularly only, never intradermally.


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