What does a normal anion gap (AG) (ie, hyperchloremic acidosis) indicate?

Updated: Aug 20, 2020
  • Author: Antonia Quinn, DO; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Normal AG (ie, hyperchloremic acidosis) indicates the following:

  • GI loss of HCO3-, diarrhea

  • Pancreatic fistula

  • Renal HCO3- loss - Type 2 (proximal) RTA

  • Renal dysfunction

  • Some cases of renal failure

  • Hypoaldosteronism (ie, type 4 RTA)

  • Hyperventilation

  • Ingestions - Ammonium chloride, acetazolamide, hyperalimentation fluids, some cases of ketoacidosis, particularly during treatment with fluid and insulin

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