What causes GI HCO3-loss in metabolic acidosis?

Updated: Oct 05, 2018
  • Author: Antonia Quinn, DO; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Answer

GI HCO3- loss is caused by the following:

  • Diarrhea

  • Pancreatic, biliary, or intestinal fistulas

  • Ureterosigmoidostomy

  • Cholestyramine

Renal HCO3- loss may be caused by type 2 (proximal) RTA.

Acetazolamide may also be a cause of metabolic acidosis.


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