What causes increased H+ load in metabolic acidosis?

Updated: Aug 20, 2020
  • Author: Antonia Quinn, DO; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Causes of increased H+ load include the following:

  • Lactic acidosis - Numerous causes, including circulatory failure, drugs and toxins, and hereditary causes (see Lactic Acidosis) [12]

  • Ketoacidosis - Diabetes, alcoholism, and starvation

  • Ingestions -Salicylates, methanol, ethylene glycol, isoniazid, [13] iron, paraldehyde, sulfur, toluene, ammonium chloride, phenformin/metformin, [14] and hyperalimentation fluids

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