What causes euvolemic hyponatremia?

Updated: Aug 24, 2020
  • Author: Kartik Shah, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Euvolemic hyponatremia implies normal sodium stores and a total body excess of free water. This occurs in patients who take in excess hypotonic fluids.

  • Psychogenic polydipsia, often in psychiatric patients

  • Administration of hypotonic intravenous or irrigation fluids during procedures or in the immediate postoperative period [14, 15]

  • In one meta-analysis, administration of hypotonic maintenance intravenous fluids to hospitalized children has been associated with an increased incidence of acute hyponatremia compared with administration of isotonic maintenance fluids. [16]

  • Infants who may have been given inappropriate amounts of free water

  • Ingestion of sodium phosphate or sodium picosulfates and magnesium citrate combination as a bowel preparation before colonoscopy or colorectal surgery [17]


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